Scientific research has shown that CBD may be therapeutic for a long list of conditions.
Below is the list compiled from hundreds of peer-reviewed articles in scientific journals and PubMed, an online service of the U.S. National Library of Medicine.
Of all the known remedies, CBD may actually have the longest list!
CBD OIL MAY HELP CURE THE FOLLOWING CONDITIONS
- ADD and ADHD
- Antibiotic Resistance
- Digestive Issues
- Endocrine Disorders
- Epilepsy and Seizures
- Heart Disease
- Huntington’s Disease
- Irritable Bowel Syndrome
- Kidney Disease
- Liver Disease
- Metabolic Syndrome
- Mood Disorders
- Motion Sickness
- Multiple Sclerosis (MS)
- Chronic Pain
- Osteoporosis/Bone Health
- Parkinson’s Disease
- Prion/Mad Cow disease
- Sickle Cell Anemia
- Skin Conditions
- Sleep Disorders
- Spinal Cord Injury
- Stroke and TBI
ENDOCANNABINOIDS VS PHYTOCANNABINOIDS
So how can one plant extract treat such a long and varied range of conditions?
This is thanks to the plant’s numerous (over 100!) active compounds called cannabinoids.
In fact, our bodies also produce cannabinoids. And we call them endocannabiods, from ‘endo’ meaning ‘‘internal’ in Greek. Cannabinoids found in plants are technically called phytocannabinoids. Phytocannabinoids mimic compounds which we call endocannabinoids that are produced naturally by all mammals.
- Endocannabinoids — cannabinoids produced by the human body
- Phytocannabinoids — cannabinoids produced by plants
HUMAN ENDOCANNABINOID SYSTEM
Hemp phytocannabinoids discharge their beneficial action via the Human Endocannabinoid System (HES), which was discovered back in the 1990s.
The discovery of HES is arguably the most important discovery in human physiology in the late 20th century.
The Endocannabinoid System is found in every animal, except for insects.
Scientists have found HES to be of paramount importance in our bodies. It is responsible for maintaining and controlling homeostasis, or balanced regulation of each and every system in the body. HES regulates a wide array of bodily functions, from appetite regulation to sleep patterns, moods, metabolism, immune response, the lifespan of cells and much more.
HOW ENDOCANNABINOIDS WORK
Endocannabinoids are signaling molecules or neurotransmitters. Hormones are a another, more familiar, type of neurotransmitter.
In order to understand how neurotransmitters work, let’s look at an analogy.
The brain regulates every sell in our bodies via a signalling system, akin to traffic signals we use on roads. These include street signs, traffic lights, the lines on the road and so on. Traffic signals inform drivers where they can and cannot travel, when they should stop and when they should go, how fast they are allowed to move and so on.
In the same way, human body’s nervous system connects via neurotransmitters to a wide variety of sensors to keep track of every system. If it is determined that a system has gone out of balance, the nervous system produces neurotransmitters, which travel through the bloodstream and interact with receptors on cells, instructing them to adjust their behavior.
This is the reason that CBD seems to effect such a wide range of conditions, it is one of the brain’s key aides in maintaining harmony and well-being in the body.
CB1 & CB2 RECEPTORS
HES is truly ubiquitous in our bodies. Its receptors are located throughout the human body, all internal organs and the brain. Two most widespread receptors are receptors called CB1 & CB2.
When a cannabinoid binds to a receptor, it aligns all the bodily processes to ensure their optimum, harmonious operation and regeneration.
The most important function of the CB1 is normalisation of signaling by the neurotransmitters, e.g., serotonin, dopamine (which means mood, appetite, pain) in the brain. By the activation of the CB1 receptors, their hyper-activity or hypo-activity is regulated back into balance.
CB2 are primarily associated with the immune system and found outside of the brain in such places as the gut, spleen, liver, heart, kidneys, bones, blood vessels, lymph cells, endocrine glands and reproductive organs.
While the body produces its own endogenous cannabinoids, many scientists suggest that most people are now suffering from “cannabinoid deficiency”. Without sufficient cannabinoids in our diet, the HES operates at less than optimum efficiency, resulting in a general decline in overall health. Supplementing our diets with full spectrum phytocannabinoids may be an essential component to achieving optimal health and regeneration.
LIST OF COMMON CANNABINOIDS
Here’s a list of the most common cannabinoid molecules and some of the effects they are believed to possess.
- Cannabidiol (CBD) — The ‘jewel in the crown’, completely non-psychoactive, meaning it doesn’t get you high.
- Delta(9)-tetrahydrocannabinol (THC) — the psychoactive compound that gives users a feeling of euphoria.
- Cannabichromene (CBC) — This third most common cannabinoid, non-psychoactive, is thought to have anti-inflammatory, anti-depressant and anti-fungal effects.
- Cannabinol (CBN) — Believed to act as an appetite stimulant, antibiotic, anti-asthmatic, pain reliever and sedative.
- Cannabigerol (CBG) — Non-psychoactive and used as an antibiotic, antidepressant and pain reliever.
- Tetrahydrocannabivarin (THCv) — Less psychoactive than THC and known to have neuroprotective properties.
- Cannabidivarin (CBDv) — Similar to CBD in its effects.
- Delta(8) THC — Similar to delta(9)-THC, less psychoactive and may have neuroprotective and anti-anxiety properties.
- THCa and CBDa — Compounds found in raw cannabis that are non-psychotropic and used for anti-inflammatory and antioxidant properties.
ADDITIONAL BENEFITS OF CANNABINOIDS
Although cannabinoids are mainly known for the role they play in the human endocannabinoid system, they have powerful antioxidant effects. Vitamin C is an example of a common antioxidant.
The process of metabolizing food and even breathing can produce harmful molecules we refer to as free radicals. These molecules can latch onto molecules in our cells, causing oxidation, the same process that causes metals to rust. Free radicals can harm or kill a cell and damage DNA. Antioxidant molecules such as cannabinoids can latch onto free radicals, literally neutralising rendering them harmless.